Purpose Recently, chemoimmunotherapy has become a promising approach with remarkable therapeutic outcomes. In this study, we aimed to target HIF-1α as a reshaping of the immunosuppressive tumor microenvironment (TME) in ...

Objective: Hypoxia is characteristic feature of solid tumors and the main obstacle for favorable anticancer effects in the clinic. In this regard, hypoxia-responsive systems can be used as smart nanoformulations for deep ...

Poultry industry is one of the most important industries in the world. The use of vaccination against diseases is very important and vital in this industry because it causes irreparable losses and damages in this industry, ...

Introduction: This study aims to investigate the dose-dependent effect of varenicline as an agonist of nicotinic acetylcholine receptors and a protective agent of the nervous system on cognitive impairments, inflammation, ...

مقدمه: سرطان یکی از عوامل مهم و اصلی مرگ میر در جهان می باشد. هنوز روش مناسب و کارآمد برای پیشگیری، تشخیص و درمان موثر سرطان معرفی نشده است. از مهمترین راهکارها برای درمان سرطان افزایش میزان دارورسانی به محل تومور و کاهش ...

Breast cancer is second common cancer across the world which counts predominant in modern countries And the use of chemotherapy is used as a common method for treatment, but it is not a responsive treatment, so the focus ...

Introduction: Triple Negative Breast Cancers (TNBC) is known as lethal and the most invasive breast cancers. TNBC exhibits the properties of cancer stem cells (CSCs) such as less differentiated, high metastasis, and ...

Introduction: In addition to the highly proliferating cells that make up the bulk of the tumor, a tumor has a small subset of cells with a slow, undifferentiated cell cycle called cancer stem cells (CSCs). These cells ...

Background: Bone tissue engineering (BTE) has been introduced as an alternative to conventional treatments for bone defects that do not heal spontaneously. It has recently been shown that magnetic stimulation increases ...