Risk factors for carbapenem-resistant Acinetobacter baumannii infections

Abstract

Most infections caused by Acinetobacter baumannii are nosocomial infections that often cause infections in the intensive care unit. Over the past decade, with the increasing importance of Acinetobacter baumannii in nosocomial infections, especially in the intensive care unit and burns, many studies have been conducted in different parts of Iran. Bacteria have been developed and the high prevalence of antibiotic resistance has been well demonstrated in Acinetobacter baumannii. This study aimed to investigate the risk factors for carbapenem-resistant Acinetobacter baumannii infections. Methods: In this cross-sectional study, after the approval of the Ethics Research Committee of Tabriz University of Medical Sciences, patients admitted to Imam Reza Hospital in Tabriz, whose culture was positive for Acinetobacter baumannii between October 2020 and October 2021. Patients' information was recorded and evaluated Using a checklist. Finally, patients have been divided into carbapenem resistant and carbapenem sensitive groups. Results: In this cross-sectional study, 82 patients were included in the study. Of these, 48 (58.5%) were male and 34 (41.5%) were female. The most common causes of hospitalization were COVID-19, stroke, trauma, CRF, and Guillain-Barre, respectively. In the group of patients with carbapenem-sensitive Acinetobacter baumannii, 8 patients (5.53%) were admitted to the normal ward and 7 patients (46.7%) to the ICU. There was a significant difference between the hospitalized wards of the two groups. There was no significant difference between the type of antibiotics prescribed between patients in the two groups. There was a significant difference between the outcomes of the patients in the two groups and the patients in the carbapenem-resistant group died significantly more than the patients in the carbapenem sensitive group.