Comparison of Quantitative Electroencephalography Analysis among Patients with Idiopathic generalized tonic clonic Epilepsy with appropriate and inappropriate control

Abstract

Epilepsy is known as the second most important brain disorder after stroke. Today, nearly 50 million people around the world suffer from epileptic seizures and about one third of these seizures can not be controlled with anticonvulsant drugs. QEEG has significant advantages over other functional imaging of the brain, including its relatively low cost and portability, as well as its ability to analyze neuronal function in both excitatory and inhibitory cortex activity. Therefore, we decided to conduct a study to evaluate and compare the quantitative QEEG of patients with generalized clonic epilepsy with appropriate and inappropriate control. Materials and Methods: This study is a descriptive-analytical study in which 60 patients with idiopathic epilepsy with generalized tonic-clonic seizures treated with anticonvulsant drugs who are willing to participate in the study will be included in the study. QEEG was performed in a small number of 30 patients with seizures with good control and 30 patients with seizures with poor control of QEEG. Demographic information as well as information including seizure frequency, type of medication and age of onset were recorded in all patients participating in the study. The findings obtained in QEEG were compared between the two groups of patients and the existing differences. Results: In this study, 60 people (30 with drug resistance and 30 with appropriate response to treatment) were included in the study. 19 patients (31.7%) were male and 41 patients (68.3%) were female. In the present study, in the two groups of refractory and non-refractory, there was a statistically significant difference between the leads of Theta Anterior, Alpha Anterior, Beta Anterior, Delta central, Theta central, Alpha central, Beta central, Delta posterior, Theta posterior, Beta posterior. There was. Also, 16 patients (53.3%) in the refractory group and 5 patients (23.8%) in the abnormal group had a statistically significant difference between the two (pvalue = 0.003).