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In vitro study of grape sap and lemon mix as MR cholangiopancreatography contrast agent and its effect on signal to noise ratio of routin pulse sequences of the procedure

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Date
2019-01
Author
Asgari, Mahdi
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Abstract
Abstract Introduction: Signal suppression of the gastrointestinal tract fluids in magnetic resonance cholangiopancreatography (MRCP) has been performed using various natural and chemical substances with the different MRCP pulse sequences. This study aimed to investigate the signal suppressions of the grape syrup and the grape syrup/lemon aqueous solutions in MRCP using the heavily T2-weighted sequences. Materials and methods: For this purpose, the potassium, iron and manganese contents of grape syrup were measured by atomic absorption spectroscopy. The grape syrup and the grape syrup/lemon solutions with the various grape syrup percentages were imaged using theheavily T2-weighted sequences of MRCP such as T2 HASTE thick slab , T2 SPACE and Truefisp. Results: The concentrations of potassium, iron, and manganese in grape syrup were 34.8, 2.4 and 1 g/l, respectively. The in vitro study showed significantly lower signal to noise ratio using the grape syrup samples comparing to the grape syrup/lemon. The effective signal suppression for the in vitro study MRCP was obtained using a T2 HASTE thick slab sequence. conclusion: the grape syrup solution can be used for signal suppression of the gastrointestinal tract fluid in MRCP as an oral negative contrast material. A T2 HASTE thick slab sequence produces suitable contrast in MRCP images using the grape syrup solution.
 
Abstract Introduction: Signal suppression of the gastrointestinal tract fluids in magnetic resonance cholangiopancreatography (MRCP) has been performed using various natural and chemical substances with the different MRCP pulse sequences. This study aimed to investigate the signal suppressions of the grape syrup and the grape syrup/lemon aqueous solutions in MRCP using the heavily T2-weighted sequences. Materials and methods: For this purpose, the potassium, iron and manganese contents of grape syrup were measured by atomic absorption spectroscopy. The grape syrup and the grape syrup/lemon solutions with the various grape syrup percentages were imaged using theheavily T2-weighted sequences of MRCP such as T2 HASTE thick slab , T2 SPACE and Truefisp. Results: The concentrations of potassium, iron, and manganese in grape syrup were 34.8, 2.4 and 1 g/l, respectively. The in vitro study showed significantly lower signal to noise ratio using the grape syrup samples comparing to the grape syrup/lemon. The effective signal suppression for the in vitro study MRCP was obtained using a T2 HASTE thick slab sequence. conclusion: the grape syrup solution can be used for signal suppression of the gastrointestinal tract fluid in MRCP as an oral negative contrast material. A T2 HASTE thick slab sequence produces suitable contrast in MRCP images using the grape syrup solution.
 
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http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/66547
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