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dc.contributor.advisorSalehi, Seyed Hamid
dc.contributor.advisorShirbeigi, Laila
dc.contributor.advisorFazljou, Seyyed Mohammad Bagher
dc.contributor.authorRahiminiya, Aysan
dc.date.accessioned2022-04-30T07:58:27Z
dc.date.available2022-04-30T07:58:27Z
dc.date.issued2022en_US
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/66544
dc.description.abstractEvaluating the Healing Effects of Ajuga chamaecistus ssp. tomentella, on Second Grade Burn Wounds, a Double-Blind Randomized Controlled Clinical Trial Abstract Background: Nowadays, the use of medicinal plants is on the rise mainly due to its fewer side effects and fewer treatment costs. Despite the traditional reports on the healing property of Ajugaspecies, no clinical studies have been conducted. In this study, the effect of hydroalcoholic extract cream of Ajugachamaecistusssp.tomentella (3%) had been compared with nitrofurazone cream (0.2%) on the second-degree burn wound healing. Materials and Methods: This clinical trial was performed at Motahhari Burns Hospital in Tehran. Fifty-two cases of second-degree burn patients were randomly assigned to two groups of 26 members, including nitrofurazone and Ajuga, and were bandaged daily. This study evaluated wounds based on the onset of epithelialization, healing time, post-drug irritation, primary irritation, decreased irritation, post-drug pain, primary pain, decreased pain,allergy, infection parameters, and the bates-jensenWound Assessment Tool. SPSS, version 20 were used for data analysis. Results: Based on the observed results, Ajuga cream was compared to nitrofurazone in cases of the mean day of epithelialization onset (P-value = 0.007), healing time (day) (P-value = 0.001), Post-drug irritation (P -value = 0.007), decreased irritation (P-value <0.001), post-drug pain (P-value = 0.018), decreased pain (P-value = 0.001) (all with P value less than 0.05); it was observed that Ajuga was more effectivethannitrofurazoneand there was a statistically significant difference between the two types of drugs. According to the results, the Ajuga cream (3%) can be a useful remedy for burn wounds due to the reduction in the onset of epithelialization, healing time, post-drug irritation, irritation reduction, post-drug pain, and pain reduction. However, further large clinical trials are needed to confirm these results.en_US
dc.language.isoenen_US
dc.publisherTabriz University of Medical Sciences, School of Traditional Medicineen_US
dc.relation.isversionofhttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/66542en_US
dc.subjectAjuga chamaecistusen_US
dc.titleEvaluating the healing effect of Ajuga chamaecistus tomentella on second grade burn wounds in patients referred to burn centeren_US
dc.typeThesisen_US
dc.contributor.supervisorHerizchi Ghadim, Hamideh
dc.contributor.supervisorAyati, Mohammad Hossein
dc.identifier.docno38en_US
dc.identifier.callno38en_US
dc.contributor.departmentFaculty of Traditional Medicineen_US
dc.description.disciplineTraditional Persian Medicineen_US
dc.description.degreePHDen_US
dc.citation.reviewerAraj-Khodaei, Mostafa
dc.citation.reviewerBanagozar Mohammadi, Ahad
dc.citation.reviewerBadebarin, Davoud
dc.citation.reviewerMoini Jazani, Arezoo
dc.citation.reviewerMokaberiNejad, Roshanak


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