The effects of salpingectomy during hysterectomy on ovarian reserve: before and after clinical trial

Abstract

Hysterectomy is one of the most common gynecological surgical procedures in the world, and salpingectomy is highly recommended to prevent ovarian cancer; but it effects on ovarian reserve remains unknown. Since serum levels of anti-mullerian hormone (AMH) show small changes within and between menstrual cycles, it is a reliable and strong method for assessing ovarian reserve. Therefore, the aim of the present study was to investigate the effect of uterine tubes resection (salpingectomy) during hysterectomy on ovarian reserve through assessing serum levels of AMH before and after surgery. Materials and Methods: In this study, 26 patients (34-45 years old) underwent hysterectomy with salpingectomy, and then ovarian reserve was investigated one day before surgery and three months after surgery through assessing serum levels of AMH. Finally, the obtained data were analyzed using statistical software. Results: Total of 26 patients (mean age 42.5 ± 0.41) underwent hysterectomy via laparotomy due to uterine myoma, adenomyosis and endometrial hyperplasia. Based on the obtained results, serum level of AMH after surgery was not significantly different from before surgery. Also, no significant association was observed between age of the studied women and serum levels of AMH before and after surgery.