The effect of antenatal Betamethasone on prevention of neonatal respiratory distress syndrome before elective cesarean section at term

Abstract

Respiratory distress syndrome is one of the most common diseases in premature infants and is usually caused by various causes and causes 30% of neonatal deaths in this group. One of the treatments recommended for the prevention of respiratory distress syndrome is treatment with corticosteroids, including betamethasone and dexamethasone. Respiratory problems are an important complication of cesarean section, without labor pains, and iatrogenic neonatal respiratory distress syndrome is usually followed by selective cesarean section. This highlights the importance of fetal lung maturation before cesarean delivery, especially painless delivery. Given that suffering from respiratory distress syndrome imposes a heavy financial burden on the country's health system each year, in this study we tried to examine the effect of betamethasone before cesarean section on the prevention of respiratory distress syndrome in the term pregnancy. Methods: During this clinical trial, 12 mg intramuscular injection of betamethasone was given to 80 pregnant women 48 hours before the elective cesarean section, and another 80 pregnant women were selected as the control group at the same time. Then, after reviewing the questionnaires, the obtained data were entered into SPSS.20 statistical software and analyzed and compared the neonatal outcomes examined using chi-square and Fisher tests for grouped data and independent t-test and Mann-Whitney for data. A little was done. Logistic regression analysis was also used to control the distorting factors. Significant levels of less than 0.05 (P <0.05) were considered. Results: In this study, the apgar score of neonates of the betamethasone group was better and more significant. The hospitalization of neonatal intensive care units and the time of hospitalization of infants in the betamethasone recipient group were lower and statistically significant compared to the control group (p <0.05).