Parafoveal microvascular features of refractory cystoid macular edema associated with intermediate uveitis using optical coherence tomography-angiography

Abstract

OCT Angiography is a non invasive imaging in retinal microvascular disease. this study was designed to assess the microvascular structure of macula in uveitic refractory macular edema Design: cross-sectional observational study Method and material: Fifty-five patients in all were assessed for macular microvascular structure using Optuve OCT angiography: 30 patients with intermediate uveitis-related refractory macular edema (RME group), and 25 patients with intermediate uveitis without macular edema (control group). Results: Superficial layer density in RME and control group were significantly different in whole image and parafovea (P=0.027 , P= 0.001), however there was no significant differences between the two groups in fovea superficial density (P=0.711).There was no significant difference in deep layer density between the two groups (P>0.05). there was no There was no significant difference in FAZ, FAZ perimeter, Acircularity index and Foveal vessel density in a 300-µm-wide region around FAZ between two groups (P>0.05)