Evaluation of alveolar ventilation during medical thoracoscopy assessed by End-Tidal CO2

Abstract

Medical thoracoscopy is a device for studying the pleural space, which is performed by local anesthesia and sedative injection in a supine position without the need for anesthesia and intubation.The patient is also sedated during medical thoracoscopy with midazolam and fentanyl..Impact on respiratory muscle and respiratory drive causes changes in alveolar ventilation. Therefore, the main purpose of this study was to evaluate the effect of thoracoscopy on alveolar ventilation to compare pre- and post-procedure ventilation. Methods & Materials In this study, 36 patients with pleural effusion , whose cause was not identified by initial fluid analysis,were included in the study in the absence of contraindications for medical thoracoscopy. All patients underwent intravenous midazoal and fentanyl injections with the aim of creating light sleep and not feeling pain. Before ,during and after the procedure, the amount of carbon dioxide at the end of exhalation and o2 saturation, respiratory rate and other information were recorded. Results According to the statistics, the amount of CO2 exhaled before and after the procedure is not different (P value: 0.77). There was a statistically significant difference between the respiratory rate during and after the procedure and the pre-procedure respiratory rate was higher. The amount of oxygen saturation was not significantly different in the three time stages. The age of the patients had no effect on expiratory carbon dioxide ( P value: 0.38 ).The type of sedative prescribed did not have a significant effect on the amount of exhaled carbon dioxide.Between fluid output and fluid discharge in the first 24 hours after the procedure have no significant relationship with the amount of carbon dioxide exhalation during this period.(P value:0/447)