Evaluation of the frequency of infectious endocarditis after open heart surgeries in congenital heart diseases

Abstract

). The aim of this study is to evaluation of the prevalence of infectious endocarditis after open heart surgeries in congenital heart diseases. Materials and Methods: This study was a cross-sectional study and we studied all patients who underwent open heart surgery due to congenital heart disease Shahid Madani Hospital in Tabriz from 2011 to 2018 and if infected with endocarditis, they were included in the study. Gathering information through analysis of patient records and the information was recorded in a information form. The information form consisted of demographic characteristics such as age and gender, and the results of such echocardiographic findings, previous palliative cardiac surgery, type of surgery, postoperative laboratory findings, postoperative blood cultures, the type of microorganism involved in endocarditis, post-culture antibiogram, locations of infection in the heart based on echocardiographic findings antibiotics received, type of response to treatment, postoperative mortality and its causes. Results: In this study, 17 of 2221 children with congenital heart disease developed infectious endocarditis after open heart surgery. As a result, the prevalence of infectious endocarditis after open heart surgery in children with congenital heart disease was 0.77%. Their mean age was 2.6 (±3.4) years. Among the congenital heart disease cases, TOF was the most frequent in 4 (23.5%) cases. Pseudomonas aeruginus was the most frequent microorganism involved in 4 cases (23.5%). The most frequent antibiotics were vancomycin in 11 cases (64.7%). The most common site of infection in these patients was pulmonary valve with 7 cases (41.9%). The mean (SD) duration of surgery was 4.2 (1.3%) hours. Of these patients, only one (5.8%) died. Amikacin and co-trimoxazole had the highest sensitivity and resistance antibiotic in 9 (52.2%) and 8 (47.1%) patients, respectively. In all cases, there was evidence of vegetation in the echocardiogram