The etiologic evaluation and antibiotic resistance pattern in children with acute bacterial Meningitidis after Heamophilos Influenzae type-b vaccination

Abstract

The aim of this study was the etiologic evaluation and antibiotic resistance pattern in children with acute bacterial Meningitidis after Heamophilos Influenzae type-b vaccination. Materials and Methods: In this study, which is a descriptive epidemiological study between 93-97, the demographic characteristics including age, sex, weight and height, and the results of CSF culture evaluation on the type of bacteria as well as antibiotic resistance patterns (antibiograms) all patients referred to the Children's Education and Therapy Center were registered in a questionnaire and were investigated. Results: Among the bacteria isolated from CSF cultivation in Children's Education and Therapy Center in Tabriz during 93-97, the majority of whom were boys with 26 persons (56.5%), the highest frequency was related to Pneumococcus with 9 persons (19.6%). The frequency (%) of HBV was 4 (8.7%). However, the same study that was done during 86-91 at this center, the most common bacteria isolated from CSF cultures was Streptococcus Pneumoniae and Haemophilus Influenzae with 34.5% and 23.36% respectively. The highest antibiotic resistance and susceptibility to bacterial agents in patients were respectively SXT (Sulfamethoxazole and Trimethoprim) and C (Chloramphenicol) respectively.