Short and Long-term Mortality in Severe Sepsis/Septic Shock in a Setting with Low Antibiotic Resistance

Abstract

The aim of this study was to evaluate the short-term and long-term mortality in patients with severe sepsis and septic shock in centers with low antibiotic resistance. Materials and Methods: In this cross-sectional study, 100 patients with severe sepsis and septic shock were included. Blood culture samples and peripheral blood samples were taken from all patients for para-clinical tests. The severity of severe sepsis and septic shock was assessed by the APACHE II and SOFA clinical criteria. Sepsis risk factors and primary causes of sepsis were recorded. Results: From 100 patients, 55% had severe sepsis and 45% had septic shock. Comparison of severity of sepsis between two groups of severe sepsis and septic shock showed that SOFA24h and SOFA96h scores were significantly higher in patients with septic shock. In sepsis risk factors, it was found that alcohol usage in patients with septic shock was significantly higher than patients with severe sepsis. In the clinical findings of patients, the most common primary cause of sepsis was related to abdominal infections with a frequency of 42%. The frequency of confirmed positive blood culture was 53%. The most commonly isolated pathogen was E. coli with a frequency of 66%. Short-term mortality was 29% and long-term mortality was 28.2%.