Randomized Controlled Clinical Trial to Identify the Effect of Information Prescription in Reducing Relapses in Patients with Inflammatory Bowel Disease

Abstract

Abstract Introduction: The prevalence of inflammatory bowel disease is increasing in our country, according to gastrointestinal experts, and as these diseases cause many complications and lower quality of life, patients need to be more careful. Objective: The aim of this study is to evaluate the evidence-based evidence in reducing relapse of the disease, complications of self-sickness, the cost of relapsing disease, drug changes in patients, and comparing the quality of life of inflammatory bowel patients. Methods: The inflammatory bowel disease patients who referred to the gastrointestinal tract of Tabriz Imam Reza Hospital from January 2014 to September 2010 were randomly assigned to the intervention group from a total of 160 patients. The information was confirmed by the physician to the intervention group Subsequently, follow-up was conducted by telephone, questionnaire and referring to patients with recurrence of disease and other purposes. Data analysis and analysis was performed on descriptive statistics and statistical tests such as Chi-square test and in two analysis The variables of Mann-Whitney's parametric and nonparametric tests, Kaplan-Meier and Cox multivariable regression models The statistical software used was STATA v.11. Results: The study showed that the patients in the intervention group had less recurrence than the control group. The cost of relapse in the control group is almost twice as high as the cost of the intervention group. Information management has been able to reduce drug use in the intervention group. Also, the information package has been able to improve the quality of life in the intervention group compared to the control group and reduce stress and self-confidence in the intervention group. Conclusion: The results of the present study provide evidence that the provision of health information services in the clinical setting can be added as a complementary health-care and improvement in the treatment process to medical services.