| dc.contributor.author | Falahatgar, Dianoosh | |
| dc.date.accessioned | 2019-01-06T09:53:16Z | |
| dc.date.available | 2019-01-06T09:53:16Z | |
| dc.date.issued | 2017 | en_US |
| dc.identifier.uri | http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/59542 | |
| dc.description.abstract | PCR and restriction digestion verified the integrity of the immunotoxin construct. Purification by affinity column resulted in a highly purified recombinant immunotoxin. MTT assay revealed the growth inhibitory effect of huscFv-PE40 immunotoxin on EGFR-overexpressing A431 cells with an IC50 value of 250 ng/ml. | en_US |
| dc.language.iso | fa | en_US |
| dc.publisher | Tabriz University of Medical Sciences Faculty of Advanced Medical Science | en_US |
| dc.relation.isversionof | http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/59541 | en_US |
| dc.subject | Immunotoxin | en_US |
| dc.subject | Pseudomonas exotoxin A | en_US |
| dc.subject | EGFR | en_US |
| dc.subject | HuscFv | en_US |
| dc.title | preparation of anti-EGFR scFv-PE40 exotoxin and evaluation of its cytotoxicity on EGF expressing tumoral cells | en_US |
| dc.type | Thesis | en_US |
| dc.contributor.supervisor | Farajnia, safar | |
| dc.contributor.supervisor | Zarghami, Nosratollah | |
| dc.identifier.docno | 159 | en_US |
| dc.contributor.department | Medical Biotechnology | en_US |
| dc.description.discipline | Medical Biotechnology | en_US |
| dc.description.degree | M.Sc | en_US |
