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The effect of storage conditions on the physical stability of tablets

dc.contributor.authorNokhodchi, A
dc.contributor.authorJavadzadeh, Y
dc.date.accessioned2018-08-26T09:39:40Z
dc.date.available2018-08-26T09:39:40Z
dc.date.issued2007
dc.identifier.urihttp://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/58320
dc.description.abstractThis article reviews the effect of moisture on the postcompaction properties of pharmaceutical solid dosage forms. It was stated that the amount of moisture adsorbed by drugs or excipients influences hardness, disintegration time of compacts and the dissolution rate of drugs. These changes may alter bioavailability and therapeutic efficacy, even though the drug potency and purity appear unaltered.
dc.language.isoEnglish
dc.relation.ispartofPharmaceutical Technology Europe
dc.subjectacetylsalicylic acid
dc.subjectcalcium phosphate dibasic
dc.subjectdiphenhydramine
dc.subjectexcipient
dc.subjecthydroxypropylmethylcellulose
dc.subjectlactose
dc.subjectmaltodextrin
dc.subjectmicrocrystalline cellulose
dc.subjectsodium chloride
dc.subjectstarch
dc.subjectsucrose
dc.subjectcrystallization
dc.subjectdrug bioavailability
dc.subjectdrug efficacy
dc.subjectdrug potency
dc.subjectdrug purity
dc.subjectdrug solubility
dc.subjectdrug stability
dc.subjectdrug storage
dc.subjecthumidity
dc.subjectmoisture
dc.subjectmolecular interaction
dc.subjectphysical chemistry
dc.subjectreview
dc.subjectsustained drug release
dc.subjecttablet compression
dc.subjecttablet disintegration time
dc.subjecttablet hardness
dc.subjecttablet porosity
dc.subjecttablet property
dc.subjecttensile strength
dc.titleThe effect of storage conditions on the physical stability of tablets
dc.typeArticle
dc.citation.volume19
dc.citation.issue1
dc.citation.spage20
dc.citation.epage26
dc.citation.epage
dc.citation.indexScopus
dc.citation.URLhttp://www.pharmtech.com/effect-storage-conditions-physical-stability-tablets


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