The effect of storage conditions on the physical stability of tablets
چکیده
This article reviews the effect of moisture on the postcompaction properties of pharmaceutical solid dosage forms. It was stated that the amount of moisture adsorbed by drugs or excipients influences hardness, disintegration time of compacts and the dissolution rate of drugs. These changes may alter bioavailability and therapeutic efficacy, even though the drug potency and purity appear unaltered.