Remedial effect of Cinnamon Zeylanicum on serum anti-oxidants levels in male diabetic rat

Abstract

Cinnamon is an antioxidant and it has been shown to reduce oxidative stress. Previous study confirmed antioxidants enzymes have imbalanced on diabetes by hyperglycemia role on reactive oxygen's spaces and is one of the male infertility agents. Wistar male rat (n=40) were allocated into four groups, control group (n=10), Cinnamon group that received 75mg/kg by gavage method, diabetic group and diabetic group that treatment Cinnamon 75mg/kg daily for 30 days respectively, however the control group just received an equal volume of distilled water daily. In 30day, 5 cc blood sample of each rat was taken for anti-oxidants measurement. serum catalase, Superoxide dismutase and Glutathione peroxidase levels significantly were increased in group that has received 75mg/kg Cinnamon in comparison to control and diabetic groups (P<0.05). Serum malondialdehyde level significantly was decreased in group that has received 75mg/kg Cinnamon in comparison to control and diabetic groups (P<0.05).Since in our study 75mg/kg Cinnamon has significantly increased serum anti-oxidants levels so it seems using it in diabetic male patients has beneficial effects.