Pulmonary maturation in preterm rupture of membranes with oligohydramnios

Abstract

The cross-sectional comparative study performed over pregnant women with PPROM and gestational age of 28-34 weeks to assess the effects of mild and severe oligohydramnios on the fetal lung maturation in preterm pregnancies with preterm PROM. In this study, average gestational ages and birth weight were not significantly different between the 2 groups with mild and severe oligohydramnios. The average duration of PPROM was more in patients with severe oligohydramnios than those with mild oligohydramnios. Also, the newborns of patients with mild oligohydramnios were at higher risk of Hyaline Membrane Disease (HMD) or Respiratory Distress Syndrome (RDS) in comparison with the newborns of women with severe disease. In both groups the highest incidence of HMD is belonging to newborns of women with PROM occurred in lower gestational age. The neonates' mortality was not significantly different in 2 groups. Also, relation of PROM-labour interval with incidence of HMD was not significant.