Outcome of cystic fibrosis in patients with bronchiectasis

Abstract

Introduction Bronchiectasis is a common problem in children especially under 5 years. Early diagnosis of disease and its causes could be useful in early treatment and preventing probable complications. This study aimed at evaluating the Cystic fibrosis (CF) in patients with bronchiectasis. Materials and Methods In a cross-sectional study, 374 children with bronchiectasis were studied. The diagnosis was made according to clinical (chronic cough and persistent sputum) and Computerised tomography (CT) scan findings. Demographic findings, clinical findings, treatment, etiology, imaging and outcome of diseas were recorded. Results Two-hundred-and-forty (64.2%) were male with mean age of 8.61±3.36 years at the diagnosis. In patients with and without the etiology of CF, the cure was observed in 1 (5.6%) and 132 (37.1%), partial remission in 5 (27.8%) and 148 (41.6%) of the cases and non improvement in 12 (66.7%) and 76 (21.3%). There was significant relation between existence of asthma (p<0.001), Gastroesophageal reflux (GERD) (p=0.02) and CF (p<0.001) with response to treatment in bronchiectasis. Conclusion Bronchiectasis is common in infants with the etiology of CF and cure and partial remission is lower in CF patients who have bronchiectasis.