Evaluating the efficacy of 99mTc- ECD radiodrug in cat's brain scintigraphy

Abstract

The aim of this study was to evaluate the efficacy of 99mTc-ECD radiodrug in cat's brain scintigraphy. In present study, 12 adult healthy cats were selected and brain scintigraphy was done with radiopharmaceutical 99mTc- ECD in these cats. In this method, the administration of radioisotopes to the body and accumulation of these substances in the target tissues, specific imaging is obtained, which is based on distribution of gamma radiations exposed from these radioisotopes and recording of them. For scintigraphy, animals were taken under anesthetic condition and 99mTC-ECD was injected from femoral vein as bolus at the 2 mCi. 20 minutes after intravenous injection of radioidrug scintigraphic operations were done. The ROIs can be drawn in all scans and radioactive counts were easily measured. Our results show that the radiopharmaceutical 99mTc-ECD has excellent evaluate the efficacy in cat's brain scintigraphy.