Effect of nibbling and gorging dietary regimens on weight and lipid profile in rat

Abstract

To investigate the effects of nibbling and gorging dietary regimens on weight and lipid profiles in rat, thirty female Wistar rats, after 10 day acclimatization period, were weighed and randomly assigned into two equal groups. They were fed the same food for 60 days as eight meals at 2 h intervals starting from 6 pm (nibbling group) or as two meals at 9 pm and 6 am (gorging group). The serum lipid levels and weight of animals were determined before and after the intervention. The body weight in two groups increased significantly (p<0.001) during the period of study but there was no significant (p>0.05) difference between two groups before and after the intervention. Nibbling regimen caused a reduction in the serum Total Cholesterol (TC), triglyceride and LDL-C levels, whereas these parameters increased during gorging diet. However, none of these changes were significant. There was a significant decrease (p<0.05) in TC and LDL-C levels in nibbling diet compared to gorging one. According to obtained results, nibbling regimen has better effect on lipid profile than gorging one in rat. © 2007 Asian Network for Scientific Information.