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  • مشاهده آیتم
  •   صفحه اصلی مخزن دانش
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  • مشاهده آیتم
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Synthesis and characterization of Zinc (II)-loaded Zeolite/Graphene oxide nanocomposite as a new drug carrier.

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تاریخ
2016
نویسنده
Khatamian, M
Divband, B
Farahmand-Zahed, F
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نمایش پرونده کامل آیتم
چکیده
Current research has focused on the preparation of Zinc-clinoptilolite/Graphene Oxide (Zn-Clin/GO) hybrid nanostructure and investigating its biocompatibility for the first time. As prepared samples were characterized by X-ray diffraction (XRD), Scanning electron microscopy (SEM), Thermo gravimetric analysis (TGA) and Fourier transform infrared (FT-IR). In order to use it as a drug carrier two important factors were investigated: cytocompatibility of nanocomposites and their drug loading capacity. The results showed that the prepared nanocomposite is cytocompatible and its high loading capacity and slow release performance for Doxorubicin (DOX), as a cancer drug, proved that it can be used as a drug carrier. At last in-vitro toxicity of DOX loaded nanocomposite was compared with pure DOX.
URI
http://dspace.tbzmed.ac.ir:8080/xmlui/handle/123456789/39957
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