Effect of photodynamic therapy and casein phosphopeptide-Amorphous calcium phosphate(CPP-ACP) on noncavited root caries remineralization(in vitro study)

Abstract

Remineralization as a treatment procedure has received a lot of attention to prevent demineralization of tooth. The objective of this in vitro study was to find out the efficacy of photodynamic therapy and Casein Phpsphopeptide-Amorphous CalciumPhosphate) CPP-ACP (on noncavitated root caries remineralization. MATERIALS AND METHODS: 72 mandible premolars were selected and divided into four groups of 18 teeth each: 1(control), 2 (Photo Dynamic Therapy), 3 (CPP-ACP) and 4 (CPP-ACP +PDT). Demineralization of samples was done bye bactery.All the samples were assessed using DIAGNOdent at the baseline and after demineralization and remineralization. Data was analyzed using descriptive statistical methods (Mean, SD) and One WayS ANOVA test by using of SPSS.16 software. RESULTS: Statistical analysis showed that group 3 (CPP-ACP) and group 4(CPP-ACP +PDT) had a significantly higher amount of remineralization than group 1(control) and 2 (PDT). According to result of this study, most reminiralization related to group 4, group 3 respectivel . and there was no significant different between group 1,2. CONCLUSION: 3 and 4 groups showed a statistically significant amount of remineralization. However, because of the added benefit of PDT to CPP-ACP, group 4(CPP-ACP +PDT) showed more amount of remineralization than 3 (CPP-ACP). Also, there were no difference statistically between control group and PDT group.