School of Pharmacy

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The School of Pharmacy, as the second pharmacy faculty in Iran after Tehran pharmacy school in 1328 Hejri Shamsi , was located at Tabriz Imam Khomeyni square and Ayatollah Taleghani Street ,was established to provide the country needs to pharmacist. This major change occurs when there was no pharmacy school in Tabriz and pharmacy personnels learn it experimently and finally reach the stage of dispensering . Permission to establish a pharmacy was given after passing the test which requires the literacy and knowing Latin language and dispenesring. Tabriz pharmacy faculty is established after student advertising admission. At the first reception, the number of students did not pass, But college starts first training cources with 25 students. After 2-year curriculum of courses, the speciality pharmaceutical topics were teached. Toxicology and jalinoosi products were as specialized courses. Later by the dean Department , Dear doctor Ismaiil Anghajy , basic steps were taken for developing the faculty. School of Pharmacy began its own activities with medicine school and gained independence in 1345.following the dissolution of the pharmacy schools in whole country in September 1347, a new school of pharmaceutical and clinical laboratory sciences began its own activities.The pharmacy faculty was established with the aim of training pharmacy students and drug experts to manage pharmacy, Pharmaceutical industry,economy of country and training experts to work in clinical laboratory and searching in pharmacy and the laboratory. The Department of Laboratory science was transferred Medicine faculty in 1351. The Nutrition school within Tabriz Pharmacy Faculty began its academic activities with 39 students in 1353 and with the establishment of the health and nutrition school it was separated from pharmacy faculty in 1370. The new building for the School of Pharmacy started with an area of ​​17,000 square meters in 1386. Tabriz School of Pharmacy has more than 3000 pharmacy graduated is delivered to our country that many of them , have been efficient and effective rules in Pharmaceutical Science. currently Tabriz School of Pharmacy consists of 7 Department of Pharmaceutic, Pharmacology and Toxicology, Pharmacognosy, Pharmaceutical Chemistry, Pharmaceutical Biotechnology, Clinical Pharmacy and Food and Drug Control. Faculty Education departments and physical facilities with high knowledge of professors tries to through training programs, basic and applied researches and provide services , solve problems with use of a pharmacy modern knowledge and Significant contribution in scientific development of their own country. Training courses for PhD students starts in field of Pharmacognosy in Tabriz school of pharmacy . now 62 PhD students are studing in Tabriz Pharmacy faculty in the field of Pharmacognosy, Pharmaceutics, Pharmacology, Pharmaceutical Chemistry, Toxicology, Biotechnology, pharmaceutical and food and drug control. Tabriz Pharmacy school is located at the heart of the city where the science and art were born. preserved old town in the vicinity of modern development, its proximity to the Shahand mountain that always carrying snow and Uromiye lake and ... causes the city unforgettable for students who live and study in it.

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    Phytochemical investigation of Vitis vinifera leaves Raised in Malayer
    (Tabriz University of Medical Sciences, School of Pharmacy, 2024) Taghavi, Amirhossein; Nazemiyeh, Hossein; HamedYazdan, Sanaz
    Introduction: Vitis species are widely used in traditional medicine. Considering the relationship between the chemical compounds in plants and their observed effects, there is a need to investigate and identify the effective compounds of plants.Purpose : Until now, the attention of researchers has been focused on the grape itself and its core, and the grape leaves were often thrown away by farmers. This happens while grape leaves are a rich source of polyphenolic compounds and antioxidants. Considering the limited studies on the leaves of Vitis vinifera grape plant and the lack of domestic production of medicinal products from grape leaves, extracting and investigating the phytochemical compounds in the leaves of local grape cultivars will be innovative.Methods and materials: A sufficient amount of leaves of the plant were collected in the summer season from private farms in Malayer city (Hamadan province) and dried in the shade after washing. Dry samples were extracted by powder grinding and then by n-hexane, chloroform and methanol solvents and with the help of Soxhlet . Then their solvent was evaporated by the evaporator. The methanolic extract was fractionated and separated by various methods of solvent-to-solvent extraction and chromatography (column chromatography), and finally five pure substances were identified by NMR.Results: The following compounds were identified from the ethyl acetate fraction of the methanolic extract of this plant: rosmarinic acid 2 methyl quercetin 3-O-β-D glucopyranoside Quercetin-3-O-β-D-glucuronide 6′′-methylester phenyllactic acid kaempferol-3-O-β-D-glucuronide Conclusion: Phytochemical study on the ethyl acetate fraction of Vitis vinifera led to the isolation of five compounds. The main compound of the ethyl acetate extract of the plant is Quercetin-3-O-β-glucopyranoside, which has strong antioxidant and anticancer effects.
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    Phytochemical study on Stachys kurdica BOISS & HOHEN
    (Tabriz University of Medical Sciences, Faculty of Pharmacy, 2020) Farrokhi, Negin; Nazemiyeh, Hossein; Hamede yazdan, Sanaz
    Introduction: Stachys kurdica (Lamiaceae) is annual and perennial plant with rectangular stems, simple leaves, pistil inflorescences, radial calix, bilabial corolla and nutlet fruits in the form of ovules or spindles or linear . This plant is found in various natural habitats of Iran and especially in Golestan province from mountainous areas such as Chahar Bagh, Shahkoh, Ziarat and Golestan National Park .This plant used in the treatment of cardiovascular diseases, dermatological, gastrointestinal and used as anti-inflammatory, anti-convulsant, analgesic, etc. Goals: The aim of this study was to identify the chemical compounds in the extracts and evaluate their antioxidant activity. Methods: At first, the plant was collected from the lands overlooking the village of Sarai in the Islamic Island and after identification, the herbarium specimen was kept in the herbarium of the Faculty of Pharmacy. After drying the plant in shade and at laboratory temperature, it was extracted by n-hexane, chloroform and methanol solvents respectively in soxhlet apparatus. The dried n-hexane extract (3.65 g) was separated by decantation funnel into two methanol and n-hexane phases. Methanol phase collected (2.95 g), was subjected to vacuum liquid chromatography (VLC) using a step gradient of acetone in n-hexane (0%, 2%, 4%, 6%, 8%, 10%, 20%, 40% , 60% , 80% , 100%). The dried fractions were stained by TLC in two solvent systems. After merging similar fractions and dry and crystallize them at room temperature, the NMR method was used for identification. The MeOH extract (2g ˟3) was fractionated with SPE method by using Sep-Pack (ODS) and a step gradient methanol in water mixture (20%, 40%, 60%, 80% and 100%). These fractions were isolated by preparative HPLC and determination compounds by NMR method. Antioxidant activity of the plant was measured by DPPH on chloroform and MeOH extracts. Conclusion: Using preparative HPLC , the 40% methanolic fractions were separated and the compounds were collected according to the chromatograph pattern and retention time .by this method 2 compounds were separated and their structure were determined by ¹H,¹³C-NMR . The determined compounds were: 1) Scutellarein 7-O-β-[6”- (acetyl)] glucoside 2) Acacetin 7 –[6”( apiosyl)- 2”(acetyl)]-glucoside The results of DPPH test showed that MeOH extract of S. kurdica has more antioxidant effect in comparison to the chloroform extract.