Clinical Symptoms, Microbial Factors, Laboratory Symptoms and Outcome of Patients With Urinary Tract Infections Following Endo-Urological Procedures

Abstract

Since the share of endorological surgeries in Iran and the northwest region of Iran has increased greatly in recent years and because this issue is a new issue, no attention has been paid to infections after endorological surgeries. And after that, proper antibiotic treatment is not done for these patients; Therefore, paying attention to this issue can first determine the prevalence of this complication in this type of surgery, and then the contribution of each of these factors will be determined; Due to the fact that the prevalence and contribution of these factors remain unknown, we decided to conduct the present study with the aim of clinical symptoms, microbial factors, and the outcome of patients with urinary tract infections following endo-urological procedures. Materials and Methods: This descriptive cross-sectional study with a prospective approach was conducted by examining the clinical records of patients who are candidates for endo-urological procedures (insertion of double-J catheter, TURB, TURP, nephrolithotomy, nephrostomy) by observing the entry and exit criteria; At first, the overall prevalence of infection caused by endourological procedures was estimated; Information such as demographic information, information related to the participants' medical records, information related to disease symptoms, information related to the type of bacteria, drugs received including the type of bacteria, type of drug received, prescribed dosage, duration of hospitalization, invasive measures such as re-surgery, The need for hospitalization in the intensive care unit and mortality. Results: Gram-negative bacteria had caused diseases in a greater number of patients compared to gram-positive bacteria. Among gram-negative bacteria, Escherichia coli was the most common type, while among gram-positive bacteria, Enterococcus faecalis was the most common type. Clinical symptoms of the patients indicated that all patients had a fever above 38 degrees Celsius, and the majority of patients also experienced urinary burning. The most commonly used antibiotics in patients with double-J stents, TURB, and TURP were ciprofloxacin, imipenem, and cotrimoxazole, respectively. However, the most commonly used antibiotics in patients undergoing nephrolithotomy and nephrostomy were imipenem, meropenem, and ciprofloxacin, respectively. The most frequently isolated strains from urine cultures were Escherichia coli and Pseudomonas aeruginosa. The highest resistance to Escherichia coli was observed against cotrimoxazole (75 cases), ceftriaxone (41 cases), and amikacin (41 cases). Furthermore, the highest resistance to this bacterium was found against cotrimoxazole (69 cases), ceftazidime (66 cases), cefepime (36 cases), cefepime (36 cases), piperacillin-tazobactam (36 cases), and gentamicin (31 cases).