Investigating the antibiotic prescription pattern in the treatment of neonatal sepsis based on the frequency of the microbial agent in the NICU department of Al-Zahra Hospital

Abstract

Introduction: This study is done on neonatal with sepsis. we will study the patient's medical records and check the pattern of antimicrobial agents administration for treatment of neonatal sepsis according to pathogens.Objectives: To study the pattern of antimicrobial agents administration for treatment of neonatal sepsis according to pathogens in NICU of Alzahra Teaching Hospital .Methods: In this research, we examined the records of patients who were hospitalized in this department in the year 1400 and received antibiotics. A checklist containing this information was recorded for each patient: demographic information, risk factors during pregnancy, Apgar score at birth, under respiratory assistance, short-term outcomes, type of antibiotic received, dose and duration of antibiotic received. Also, this information was retrospectively extracted from the patients' records and recorded from the findings. These data were put in spss-24 software and using relevant statistical methods, the records were analyzed. Results: Examining the treatment process for neonates with early onset sepsis showed that the type of antibiotic was prescribed correctly in all cases, but there were some minor differences in the dosage of antibiotics.Conclusion: Based on the findings of this research, the process of treating early-onset neonatal sepsis has progressed in choosing the type of antibiotic and the length of the treatment period based on the protocol, and the highest number of inconsistencies is in the dosage of antibiotics, and since it seems that the accuracy And accuracy in the dosage of prescribed antibiotics has a significant effect on the recovery rate and the length of the hospitalization period of newborns, increasing the compliance of the treatment process with the proposed localized protocol is necessary.