Comparison of blood sugar changes during anesthesia of orthopedic elective limb surgery in obese and non-obese patients

Abstract

Blood sugar changes in different ways in different people at different times such as before surgery, during surgery, and after due to different reasons; In other words, different factors are involved in blood sugar changes. One of these changes can be attributed to obesity. Since the prevalence of obesity has increased sharply in recent decades, the prevalence of orthopedic procedures has also increased in obese people; obesity is one of the causes of disorders in the glandular system, including that obese people are more exposed than non-obese people. having diabetes and blood sugar changes; But whether these people are prone to blood sugar changes during surgery has not yet been confirmed; Therefore, in this study, we decided to compare blood glucose changes during anesthesia for elective lower limb orthopedic surgery in obese and non-obese people. Methods: This case-control study was conducted in Tabriz University of Medical Sciences during 2021 with the participation of 90 patients (45 = case group = control group) candidates for orthopedic surgery. Patients' blood sugar was measured before transfer to the operating room, before induction of anesthesia, immediately after surgical incision, and 45 minutes after surgery and at the end of surgery, as well as during recovery. On the other hand, the hemodynamic status of the patients was also measured at intervals of every 5 minutes during the anesthesia of the patients and finally compared between the two groups. Results: Comparison of blood sugar level between two groups before surgery (P=0.099) was without significant statistical difference; However, blood sugar level before anesthesia (P=0.049), immediately after surgical incision (P=0.044), 45 minutes after surgical incision (P=0.031), at the end of surgery ( P=0.033) and during discharge from recovery (P=0.041) in the group of obese patients was significantly higher than the group of non-obese patients; Comparison of blood sugar changes in obese patients with the help of ANOVA test indicated that these changes are significantly associated with an increase (P=0.019), while these changes were without significant changes in the group of non-obese patients (P=0.312).