Impact of Iron deficiency on in-hospital and six months outcomes of patients with acute STEMI treated with primary PCI

Abstract

Iron is both an essential nutrient and an environmental toxin. Iron is essential for oxygen transport and cellular oxidation. Several lines of evidence have shown that iron-deficient anemic patients have worse outcomes after acute myocardial infarction (AMI). However, few studies have fully investigated this issue. The purpose of this study was to investigate the effect of iron deficiency anemia on hospital and 6-month clinical outcome of acute STEMI patients who underwent primary angioplasty. Method: In this prospective cross-sectional study, patients with acute STEMI who visited Shahid Madani Hospital in Tabriz between October 2020 to October 2022 and underwent PPCI (257 patients) were included in the study, and the characteristics of patients with and without iron deficiency of the group Including in-hospital MACE and 6 months, TIMI flow at baseline and after PPCI and Enzymatic infract size were compared with each other. Results; The investigations carried out in this study showed that there was no significant difference in terms of any of the demographic characteristics between the patients of the two groups. The only case of disease history that was significantly higher among patients with iron deficiency was anemia history (p<0.001). No significant difference was found in terms of drug records and vital signs between the studied patients. Also, the patients of the two groups were not significantly different in terms of STEMI characteristics and angiographic findings. In-hospital and 6-month complications of the patients were not significantly different between the two groups.