Prevalence of aortopathy at the time of diagnosis and 5 years after diagnosis in patients with congenital heart disease

Abstract

A dilated aorta is associated with a decrease in elasticity and an increase in stiffness of the aortic wall, which has negative effects on the systolic and diastolic functions of the ventricles, because it causes an increase in ventricular overload and hypertrophy. In this study, considering the vital complications of aortopathy, we investigated the prevalence of aortopathy in patients with congenital heart disease. Also, the rate of progression of this disease after 5 years in two groups of cyanotic and asianotic patients and the difference in the prevalence of aortopathy in patients who underwent reconstructive surgery and patients who did not undergo surgery were investigated.. Materials and Method: During this study, based on the calculated sample size, 120 children were included in the study, of which 18 died during the study and were excluded after the study, 82 congenital disease patients referred to Tabriz Children's Hospital and Shahid Madani . . The required information was extracted from the file. Then, all patients underwent echocardiography by a pediatric heart specialist. The indicators investigated in echocardiography include aortic annulus diameter, sinuses of Valsalva, sinotubular junction and ascending artery. Finally, the obtained data were statistically analyzed by SPSS software. Results: According to the results of our study, the prevalence of arthropathy at the time of diagnosis was higher among asianotic patients than cyanotic patients. On the contrary, in comparison after 5 years, we observed that the prevalence of arthropathy in the cyanotic group was higher than in the asianotic group, which can indicate a higher incidence of arthropathy in cyanotic patients over time. In addition, the disorder in all investigated indicators in both cyanotic and asianotic groups increased after 5 years compared to the time of diagnosis. In the 5-year follow-up and comparison between the operated and non-operated patients, we observed that there was no difference in the Asianotic group between the operated and non-operated groups. On the other hand, the disorder of cyanotic patients who underwent surgery was higher in annulus diameter, ascending aorta and Valsalva indices, compared to the non-operated group.