TSH association with incidence of stroke and its types in patients diagnosed with stroke in Emam Reza hospital of Tabriz
Abstract
Stroke is the second leading cause of death and the first cause of disability worldwide. Disability following a stroke leads to the loss of normal life for individuals, with most stroke survivors needing care and assistance for their daily activities. Considering the significant impact of thyroid hormones on cellular metabolism, an expected relationship between TSH and the occurrence of stroke is plausible. Previous studies have shown a correlation between TSH and an increased risk of cardiovascular diseases, but the association with the risk of stroke has yielded conflicting results.
Materials and Methods: In this cross-sectional study, 205 patients admitted to Imam Reza Hospital from March 2021 to February 2023 with a confirmed stroke diagnosis were consecutively selected. Necessary data was extracted and recorded from the stroke registry. Statistical analysis was performed using SPSS22 software. In this study, a P value less than 0.05 was considered statistically significant, and a 95% confidence level was applied for the statistical tests. Our purpose of this study is to play a role in collecting information and filling the gap and find the relationship between Thyroid disorders and the incidence of stroke.
Results: Out of 205 samples included in the study, 34 cases of hemorrhagic stroke (16.6%), 151 cases of ischemic stroke (73.7%), 9 cases of TIA (4.4%), and 11 cases of CVT were reported. Among the 205 patients examined, 35 individuals (17.1%) had TSH levels below the normal range, 155 individuals (75.6%) were within the normal range, and 15 individuals (7.3%) had TSH levels above the normal range. The median TSH measured in this study was 2.05 with an interquartile range of 1.3 for stroke patients.