validity and reliability of persian version of Cambridge-Hopkins Diagnostic Questionnaire for RLS (CHRLSq)

Abstract

Restless leg syndrome, also known as Willis-Eckbom's disease (RLS/WED), is a common condition. The Cambridge Hopkins Diagnostic Questionnaire for RLS (CHRLSq) is a good diagnostic tool and can be used in epidemiological studies. However, its Persian version is not available. Therefore, this study was conducted to translate and validate it in the Persian-speaking Iranian population. Methods Sampling was purpose-based, so that people with restless leg syndrome who referred to Imam Reza Center or private practice were included in the study. Confidentiality of information, after obtaining informed consent, they proceeded to complete the questionnaires. In order to determine validity based on content validity index (CVI) and content validity ratio (CVR) about the content, clarity and simplicity of the questionnaire questions were used. In order to determine the reliability, the questionnaire was completed by all the people in the study at an interval of about 14 days, and the intraclass correlation index (ICC) and its confidence interval were calculated between the scores obtained from answering the instrument twice for each factor and the entire questionnaire. In order to determine internal consistency, Cronbach's alpha coefficient was used for each factor and the entire instrument. SPSS21 software was used for calculations. Results The results of the present study showed that the number of women with RLS/WED was more than men. The highest frequency of underlying disease in the studied subjects was kidney disease and diabetes mellitus. Eighty-two percent of patients were taking medicine. People with a history of covid-19 made up 50.7% of the participants. Cronbach's alpha coefficient of 0.750 obtained for the questionnaire showed that the current questionnaire has the necessary reliability. Also, in our evaluation, CVI for most dimensions of the questionnaire was equal to one and most of the items were considered relevant. In terms of CVR, most of the criteria of the questionnaire scored high.