outcomes of percutaneous biliary drainage (PTBD) in patients with tumoral obstructive jaundice

Abstract

PTBD is a relatively easy procedure and treatment with a high success rate in reducing biliary pressure. PTBD leads to complications in 10% of cases, ranging from minor (eg, access site pain) to normal. PTBD has a relatively low complication rate, and those that do occur are usually self-limiting. Methods: This study was performed retrospectively on all patients who underwent PTBD due to inoperable, malignant, symptomatic and biliary obstruction. PTBD method, catheter type (10F, 8F), number of additional catheters, serum bilirubin level after PTBD, minor or major side effects PTBD and patient survival or death and the time from PTBD to death were investigated. Results: A total of 453 patients were included in the study. The average age of the patients was 63.24 ± 13.04 years in the range of 18 to 90 years, and in terms of gender distribution, 219 cases (45.8%) were male and 234 cases (49%) were female. The average bilirubin before PTBD was reported as 10.61±17.47 and after PTBD as 8.81±12.49. No case of patient death following the procedure was reported. The frequency of complications was as follows: 7 cases of catheter bleeding, 2 cases of obstruction, 10 cases of catheter displacementleading to 5 case of biliary leak (2 case of biloma and 3 case of billiary peritonitis) 1 case of pancreatitis, 1 case of portobiliary fistula, and 1 case of arteriobiliary fistula were reported. The highest frequency of complications was related to cholangiosarcoma. The type of tumor causing obstruction had a significant relationship with the occurrence of complications related to access, vascular and non-vascular (P<0.05), but no significant relationship was reported with complications related to the catheter (P>0.05).