Evaluation of lipid profile of patients with acute stroke referred to the emergency department and its relationship with 3-month outcome of patients

Abstract

Given that hyperlipidemia is one of the risk factors of stroke and is one of the factors that can be controlled, therefore the aim of this study is to investigate the treatment process and the effect of initial lipid profile on the outcome and length of hospitalization of stroke patients receiving thrombolytic therapy. Or we can treat the old routine as well as hemorrhagic stroke at the Imam Reza (AS) educational and treatment center in Tabriz.

method: This study is a cross-sectional and retrospective study, all patients referred to Imam Reza Emergency Department of Tabriz who were admitted with a diagnosis of stroke during 2018 and 2019 were included in the study. For all the studied patients, the information needed for the research, such as age, sex, length of stay in the hospital, initiation or non-initiation of thrombolytic therapy, history of hyperlipidemia, patient outcomes such as discharge, permanent neurological deficit or death were recorded for the patients.

Results: 2165 patients were included in this study. Based on this, the average age of the patients was 66.98 ± 15.40 (66.33-63.63, 95% CI), the median age of the patients was 69 years with a median of 56 to 78 years. In examining the gender distribution of patients, 1125 patients (52%) were male and 1040 patients (48%) were female. In examining the cholesterol level of patients during hospitalization on the day of hospitalization, the median was 154 mmol/dL of blood, and the interquartile range was 129 to 186 mmol/dL of blood. In examining the triglyceride level of patients during hospitalization on the day of hospitalization, the median was 111 mmol/dL of blood, and the interquartile range was 82 to 149 mmol/dL of blood. In examining the LDL level of patients during hospitalization on the day of hospitalization, the median was 93 mmol/dL of blood, and the interquartile range was 70 to 119 mmol/dL of blood. In the examination of the HDL level of patients during hospitalization on the day of hospitalization, the median was 36 mmol/dL of blood, and the interquartile range was 30 to 44.5 mmol/dL of blood. There is a significant relationship between gender and other variables with most outcomes, but it does not show a strong relationship. Between age and other variables, there is a significant relationship with most outcomes, but it does not show a strong relationship. There is a significant relationship between the type of stroke and other fat profiles, with most of the variables, and this relationship has a relatively good relationship with triglycerides, and with the increase of triglycerides, the probability of ischemic stroke increases.