Study of Side Effects Following Covid-19 Vaccination

Abstract

The Covid-19 infection originated in Wuhan, China in December 2019 and in a short period of time paralyzed human health globally. The public health emergency required urgent efforts to develop and test the efficacy and safety of vaccines to combat the Covid-19 pandemic. Emergency use approval has been granted to the COVID-19 vaccines before the normal stages of clinical trials have been completed. However, there is still a need for a comprehensive review of the safety of vaccines in order to reduce the perceived risk. The aim of this systematic study is to provide comprehensive data of the evidence of the relationship between the side effects caused by the types of covid 19 vaccination. Materials and methods :This study followed PRISMA guidelines. We searched PubMed, Google Scholar, SCOPUS, Web of Science and Embase databases for studies published between December 2020 and 2023, and among them, 4 studies were identified for review in this study. Results: Most of the studies investigated the side effects after the Pfizer-BioNTech vaccine, and most of the reported reactions were mild to moderate. The most commonly reported severe side effects include pain, swelling, and redness around the injection site and systemic effects such as fever, fatigue, myalgia, headache, allergic events, neurological events, and cardiovascular outcomes including chest pain, myocardial infarction, pressure Acute bleeding, tachycardia, myocarditis, syncope, supraventricular tachycardia, decompensated heart failure and paroxysmal ventricular tachycardia. In terms of age and gender, systemic side effects were moderate in the younger age group. Local and systemic side effects were more common after the second dose..