Factors associated with glycemic control among Azar cohort population with type2 diabetes

Abstract

Diabetes mellitus (DM) is a global public health problem that leads to about five million deaths annually. Due to the importance of glycemic status in the occurrence of diabetes complications, it is essential to know the associated factors. This study assessed the glycemic control status and its relevant factors among type 2 diabetes mellitus (T2DM) patients. Methods: In this cross-sectional study conducted among the Azar cohort population, the glycemic control status of patients with T2DM was investigated. Possible risk factors including age, sex, marital status, educational level, smoking status, sleep duration, family history of diabetes and hypertension, socioeconomic status, physical activity level, and co-existence of other chronic diseases and their relationship with glycemic control status were also assessed. Multivariate logistic regression analysis was used to identify determinants of glycemic control. Results: Among 1,744 T2DM patients (60.3% female), the overall prevalence of poor glycemic control was 56.88%. In the unadjusted logistic regression analysis model, a low wealth score index significantly increased the risk of poor glycemic control (OR: 1.49;1.10–2.01). Variables significantly associated with poor glycemic control even after adjusting for confounding factors were first-degree family history of diabetes (OR: 1.34; 1.09–1.65), diabetes duration (OR: 2.30; 1.84–2.88 for 5-10 years, and OR: 1.86; 1.42–2.45 for>10 years), and sleep duration (OR:1.24; 0.99–1.56 for 6.5-8 h/d and OR: 1.40;1.08–1.81 for >8 h/d). Participants with controlled glycemia had a higher prevalence of hypertension, stroke, COPD, rheumatoid disease, and obesity, and the percentage of patients with three or more chronic diseases was significantly higher in these subjects (P<0.001).