Comparison of anesthesia with lidocaine and diphenhydramine syrup with no anesthesia on the skin before venipuncture

Abstract

Due to the fact that there is no study in adults on the amount of pain in venipuncture with larger diameter branules and in the emergency room for large reasons occasional venipuncture of large diameter branules, so we decided to design a study that can Provide relative anesthesia for venipuncture and increase patient satisfaction.

Methods: This study is an interventional study in which patients who need a vein with branol for any reason are included in the study. In this study, based on similar studies, 50 people were placed in each group. Patients with an GCS below 15 or severe pain in one area of the body and patients under 18 were excluded. All venipunctures were performed by a trained nurse. The venipuncture site was anticubital vein in all patients. In the lidocaine group, 2% lidocaine was used, in the diphenhydramine group, diphenhydramine syrup was used, and in the fourth group, EMLA was used for site anesthesia. Patients were randomly divided into 4 groups: water, lidocaine, diphenhydramine, EMLA.

Results: In comparing the age difference between these four groups, no significant difference was found between the age of patients in these 4 groups (Pv = 0.993). Pain intensity showed a significant difference between the four groups (Pv <0.001). Pain intensity showed a significant difference between water group and diphenhydramine group (Pv <0.001). Pain intensity did not show a significant difference between lidocaine group and diphenhydramine group (Pv = 0.516). Pain intensity showed a significant difference between EMLA group and diphenhydramine group (Pv <0.001).