The burden of stroke and its attributable risk factors in the Middle East and North Africa region, 1990-2019

Abstract

Stroke is one of the leading causes of mortality and morbidity across the globe. Providing comprehensive data on the burden of stroke in the Middle East and North Africa (MENA) could be useful for health policy makers in the region. Therefore, this article reported the burden of stroke and its attributable risk factors between 1990 and 2019 by age, sex, type of stroke, and socio-demographic index (SDI). Methods: Data on the prevalence, death, and disability-adjusted life-years (DALYs), due to stroke, were retrieved from the Global Burden of Disease (GBD) study 2019 for the 21 countries located in the MENA region from 1990 to 2019. The counts and age-standardised rates (per 100,000) were presented, along with their corresponding 95% uncertainty intervals (UIs). Results: In 2019, the regional age-standardised point prevalence and death rates of stroke were 1537.5 (95% UI: 1421.9 to 1659.9) and 87.7 (78.2 to 97.6) per 100,000, which represent a 0.5% (-2.3 to 1.1) and 27.8% (-35.4 to -16) decrease since 1990, respectively. Moreover, the regional age-standardised DALY rate in 2019 was 1826.2 (1635.3 to 2026.2) per 100,000, a 32.0% (-39.1 to -23.3) decrease since 1990. In 2019, Afghanistan [3498.2 (2508.8 to 4500.4)] and Lebanon [752.9 (593.3 to 935.9)] had the highest and lowest age-standardised DALY rates, respectively. Regionally, the total number of stroke cases were highest in the 60-64 age group and was more prevalent in women in all age groups. In addition, there was a general negative association between SDI and the burden of stoke from 1990 to 2019. Also, in 2019, high systolic blood pressure [53.5%], high body mass index [39.4%] and ambient particulate air pollution [27.1%] made the three largest contributions to the burden of stroke in the MENA region.