Evaluation of RDW prognostic value in Covid-19 patients

Abstract

: Coronaviruses are a family of common human-animal viruses that can cause diseases ranging from colds to acute infectious pneumonia. Monitoring of hospitalized patients shows that the risks of Covid-19 disease are associated with severe side effects such as encephalitis, coma, hypoxia, and mortality. Although many studies on hematologic parameters associated with Covid-19, most of them have focused only on differences in parameters in patients with varying severity. However, the role of predicting hematological parameters in the prognosis of patients with severe Covid-19 had not been mentioned. Therefore, in this study, the hematological parameters of acute Covid-19patients hospitalized in Imam Reza and Sinai hospitals in Tabriz were analyzed. Materials and methods: After the approval of the Research Council of Tabriz University of Medical Sciences and the ethics committee of the faculty of medicine, at the beginning of hospitalization of 138 patients with Covid-19 in Imam Reza and Sina hospitals of Tabriz, hematological tests were performed and then during treatment, the severity of their disease, including loss of consciousness, respiratory distress due to hypoxia, death, etc. in the environment Clinically observed. Powerful SPSS and PRISM GraphPad software were used for statistical analysis. Results: Finally, according to the results of 123 discharged patients and 15 patients who died of COVID-19, this study showed that none of the blood factors studied in this study including white blood cell level, hemoglobin, RDW, CRP, MCHC, platelets, RBC, Hct, MCH and MCV were significantly different between these two groups of patients (p> 0.05). In the study of demographic factors, after controlling the effect of confounding factors, patients' age was the only factor affecting patients' mortality (p = 0.01).