Association of Body composition with Bone density and Quality of Life in Postmenopause suffering from Primary Osteoporosis

Abstract

Osteoporosis is also known as a silent or hidden epidemic in the scientific literature due to its high prevalence worldwide and the increasing number of patients. Due to the importance of recognizing, treating and preventing this disease and the lack of studies in this field, the present study was conducted to determine the relationship between body composition and bone density and quality of life in postmenopausal women with osteoporosis. Methods: This descriptive-analytical cross-sectional study was conducted on 109 postmenopausal women aged 50-65 years by simple random sampling in Tabriz health centers from September 2018 to July 2019. Bone density was assessed by dual energy X-ray absorbometry. Informed consent was obtained from all the patients and the questionnaires were completed. They were referred to the Physical Medicine and Rehabilitation Research Center. Data were analyzed using SPSS software version 24 and descriptive statistical methods: Pearson correlation test, Kolmogorov-Smirnov test, one-way ANOVA, independent t-test, Spearman test and linear regression. Results:. In the statistical analysis, there was a significant difference between the income level of the subjects and their quality of life score (P-value = 0.007). The mean (SD) bone mass density in the femoral neck was significantlly higher in married people than in single people (P-value = 0.026). There was a significant negative relationship between the number of pregnancies and the bone mass density of the femoral neck (P-value = 0.038 , r = - 0.2). There was no significant relationship between quality of life of women in the study with body composition indicators (P-value> 0.05). There was a significant positive relationship between femoral neck bone density and body weight(P < 0.001 r =0.380), body fat percentage(P = 0.018 r=0.229), body fat mass(P=0.001 r=0.317), visceral fat mass(P=0.002 r= 0.229), mineral content(P=0.001 r=0.313), total body water content(P = 0.049 r= 0.19) and body mass index (P= 0.004 r=0.278) but there was no significant relationship between bone mineral density of lumbar vertebrae with body compositiona (P-value > 0.05).