Survey of outcome of neonates with sever hyperbilirubinemia at 24 to 36 months

Abstract

Hyperbilirubinemia is a common problem and is often benign in infants. Jaundice is seen in about 60% of term neonates and 80% of preterm infants in the first week of life. Yellow color is usually caused by the accumulation of non-conjugated and fat-soluble bilirubin pigments. Aim: The aim of this study was to determine the outcome of neonates with severe hyperbilirubinemia at 24 to 36 months. Materials and Methods: In this descriptive-analytic study, newborns who referred to Tabriz Pediatric Hospital from April 1, 2003 to March 29, 2003 were admitted to hyperbilirubinemia. Sample size and sampling method were used in all of the centric neonates referring to the children's center. In the study period, 180 cases were estimated, with about 30-100 cases not referred to or died. Results: We studied 52 neonates (43%) and 69 boys (57%) in our study. Mean ± standard deviation of incidence of icter in neonates was 4.14 ± 1.27 days. The mean ± standard deviation of birth weight of newborns was 352.22 ± 255.27 grams. Among the patients, 3 (2.47%) patients suffered from ASQ score and in developmental progression, of which 3 patients (2 (1.6%)) had transfusion, one of them was due to ABO incompatibility Which received two IVIGs. 24 patients (19.83%) had a history of transfusion and all patients received invasive phototherapy. Of the 24 patients (19.83%) who had blood transfusion, 8 cases (61.6%) had evidence of ABO incompatibility, which they received after IVIG transfusion. The most common cause of hospitalization after the neonatal period was respiratory symptoms with an incidence of 10 patients (21.27%) and then fever with the frequency of 8 patients (17.02%). The highest frequency of septic symptoms was related to poor feeding with a frequency of 15 patients (65.2%). The mean ± standard deviation of bilirubin was 21.294.41 mg / dl in the first time and 5.5 ± 0.9 mg / dl in the last turn.