Study on etiology and clinical features among neonates admitted in NICU Tabriz Iran

Abstract

Considering that the neonatal period is one of the most important periods of brain development and seizures at this age can have many effects, and due to the fact that different studies in different countries and even in different provinces of our country, differences They show a lot and due to the lack of a similar study in the region, the aim of this study was to determine the causes and clinical features of neonatal seizures in patients admitted to the NICU ward of Tabriz Children's Hospital. Materials and Methods: In this previous cross-sectional study, after obtaining the code of ethics by referring to the archives of Tabriz Children's Hospital, the files of patients who were admitted to the NICU with a diagnosis of neonatal seizures from 2016 to 2019 evaluated and patient information including age, sex, birth weight, gestational age, type of delivery, Apgar score, serum electrolytes, type of seizure, family history, mortality and length of hospital stay and cause of seizure were entered in the data collection form. In this study, the clinical outcome of patients with mortality and length of hospital stay were assessed. Results: In this retrospective cross-sectional study, the clinical records of 100 infants under 28 days of age who were referred to Tabriz Children's Hospital with a primary complaint of neonatal seizures were examined. After clinical examination and evaluation of patients, neonatal seizures were R/O in 24 patients and finally 76 patients were studied. EEG findings were absent in 24 patients (31.6%) abnormal, 11 patients (14.5%) mildly abnormal, 25 patients (32.9%) normal and 16 cases (21.1%). The mean duration of hospitalization was 9.90±7.44 days (ranging from 1 to 35 days) and there were 6 cases (7.9%) mortality. The most common etiology of neonatal seizures was HIE (59.2%).