The association between severity of chronic periodontitis and knee osteoarthritis among patients referred to cilinical wards of tabriz Faculty Of Dentistry ,year 2021: Analytical study

Abstract

Introduction: Previous studies show the relationship between periodontitis and knee osteoarthritis. However, there are few studies on the correlation between knee osteoarthritis and periodontitis. Also, the results of these few studies are also different. Therefore, in this research work, due to the importance of genetic influences, life patterns in different cultures, the lack of studies in this regard in Iran, and the high prevalence of these two diseases in our country, we decided to investigate the relationship between knee osteoarthritis and periodontitis. if there is a connection between these two diseases, it is possible to reduce the treatment costs and the economic burden of osteoarthritis on the health system and the possible permanent damages of osteoarthritis with early diagnosis. This will lead to an increase in the quality of life of patients. materials and methods: In this study, 151 patients referred to the Faculty of Dentistry were studied. The diagnosis of periodontitis and its severity was based on the CAL index, and the diagnosis of knee osteoarthritis was made using the self-report questionnaire of osteoarthritis, so that the need for a rheumatology specialist to investigate the possible problem of osteoarthritis was checked. Finally, after collecting the data, the results of descriptive statistics were reported in the form of frequency and percentage for qualitative variables and as (mean + standard deviation) for quantitative variables, and descriptive statistics separately for each category in the variables of periodontitis and osteoarthritis. For review The mean age (quantitative) and BMI variables among the osteoarthritis variable categories were used by independent t-test, the mean age (quantitative) and BMI variables in the periodontitis variable categories were analyzed by one-way analysis of variance and Tukey's post hoc test. The effect of each variable was first univariate logistic regression, then multivariate logistic regression was used to control the effect of confounding variables. All analyzes were performed using SPSS version 26 statistical software. Significance level in all tests - P<05.0 value in considered Results: In the studied patients 53.6% (81 people) were male and 46.4% (70 people) were female, 67.5% (102 people) of the patients were diagnosed as unlikely to have osteoarthritis and 32.5% (49 people) of the patients were diagnosed as definitely suffering from osteoarthritis. The chance of definite disease of osteoarthritis in patients with periodontitis with severe severity was 19.67 times that of patients with periodontitis with mild severity (OR = 19.67, 95% CI = (6.50 - 59.53), p-value<0.001) by controlling demographic characteristics. The probability of osteoarthritis in patients with moderate periodontitis was 3.76 times higher than that of patients with mild periodontitis (OR = 3.76, 95% CI = (1.09-12.95, p-value<0.001)) by controlling demographic characteristics. In patients with severe periodontitis, it was 14.96 times more than in patients with mild periodontitis (OR = 14.96, 95% CI = (5.55 - 40.31), p-value<0.001). The average was 3.93 times that of patients with mild periodontitis (OR = 3.93, 95% CI = (1.22 -12.72, p-value<0.001). Conclusion: A significant relationship was found between the severity of periodontitis and osteoarthritis.