Outcome of stroke patients with renal failure and comparison with normal renal function patients

Abstract

The prevalence of stroke and subsequent disability in CKD patients with and without dialysis has not been systematically studied. The effects of age, gender, and other comorbidities, including hypertension and diabetes, on stroke in CKD patients have also not been studied. Therefore, the aim of the present study was to determine the outcome of stroke patients with chronic renal failure compared to normal renal function. Methods: All patients referred to Imam Reza Emergency Department of Tabriz who were hospitalized with stroke during 2018 and 2019 were included in the study. Demographic variables including age, sex, type of stroke (hemorrhagic or ischemic), underlying diseases, medications, history of previous stroke were recorded for all patients. Serum creatinine of patients was measured at the beginning of hospitalization. Other patient tests including serum fat and glucose profiles were also measured. GFR was then calculated for patients. Results: Results: In this study, in which 349 people were included, the mean age of patients was 70.41 ±13.77 years, the median age was 73 years and the mean age of the population was between 63 and 81 years. Of these patients, 232 patients (66.5%) were male and 117 patients (33.5%) were female. The median creatinine of patients was 1.03 mg / dl, which ranged from 0.87 to 1.30. In the GFR evaluation of patients, the median was 55.69, which was in the intermediate range of 41.68 to 78.21. In the study of pre-disease mRS among patients in the two groups, pre-disease mRS was higher in the group with abnormal GFR. In the evaluation of mRS at the last visit among the patients of the two groups, mRS is higher at the last visit in the group with abnormal GFR. In the study of mRS in patient follow-up among patients in the two groups, mRS is much higher in patient follow-up in the group with abnormal GFR