Relation between carbon monoxide level and clinical outcome of patients with asthma attack or COPD admitting to emergency department of the Tabriz Sina Hospital in 2019-2020

Abstract

However, due to expiratory CO, it may be related to serum CO level and whether serum CO is elevated in asthmatic patients so far, it has not been investigated in this study to evaluate the level of serum carbon monoxide in patients with asthma or COPD. We will also look at its association with the severity of symptoms and their clinical outcome Materials and Methods: This is a cross-sectional study in which all patients presenting with asthma attack or COPD exacerbation referred to the emergency department of Sina Hospital in Tabriz between September 2019 and August 2020 were enrolled. Demographic data including age, sex, place of residence, as well as duration of asthma, medications used were recorded. The severity of asthma attack and the percentage of serum co were measured by a Portable CO monitor (Bedfont Scientific piCO + Smokerlyzer (Pico +), UK). Clinical outcome of patients including ICU admission, ward admission, emergency discharge as well as duration of hospitalization, mortality rate and intubation rate were also assessed and their relationship with serum CO was also evaluated. Results: In this study, 131 patients were studied, of which 50 patients referred due to asthma attacks and 81 patients due to COPD Exacerbation. In this study, the mean serum levels of carbon monoxide in asthma patients were equa4.95±1.54 and its mean in COPD patients is 5.65±1.69. In the present study, there was a significant relationship between serum carbon monoxide content and hospitalization in ICU in asthma and COPD patients. Also, significant saturation of hemoglobin carbon monoxide and asthma severity were found.