Assessment of the incidence of thromboambolic events in patients during first year of prostetic valvular replacment with biologic prostetic valve

Abstract

Thromboembolism is one of the most important causes of mortality and morbidity in the world. Heart valve replacement surgery has been performed for many years and is used in cases where valvuloplasty cannot solve the valve problem. Despite many successes using artificial valves, these valves may also have complications in the short or long term. The aim of this study was to determine the prevalence of thromboembolic complications of biological valve during the first year after surgery in patients with valve replacement surgery.

Materials & Methods: The present study was a retrospective cross-sectional study. All patients who underwent cardiac valve replacement between 2006 and 2016 were included in the study and their background diseases and demographic information such as age, sex were extracted from the records and the prevalence of thromboembolic complications in the field of biological valve replacement surgery was investigated after 3 to 12 months after surgery.

Results: In this study, 165 patients were included in the study. Among them, 76 (46.1%) were male and 89 (53.9%) were female, out of 165 patients included in the present study, 7 patients (4.2%) had thrombombolic complications and 158

patients (95.8%) had no thromboembolic complications,. In the study of patients, the most common cause of valve replacement was hypertension with a prevalence of 38.2%. there was no significant relationship between history of hypertension, hyperlipidemia, history of DVT, previous pulmonary embolism history or history of ischemic cardiac or ischemic brain events with thromboembolic events. There was no significant relationship between aortic valve or tricuspid valve involvement, history of endocarditis , history of rheumatic fever disease with thromboembolic events. In the study of mitral valve involvement as a defective valve with incidence of thromboembolic events ,in the group with thromboembolism events including 5 (71.4%) cases of mitral valve replacement and the group without thromboembolic events including 73 (46.2%) cases of mitral valve replacement .difference between the two groups was statistically significant and there was a significant relationship between the two groups. (0.012=P)