Determination of anti-HPV diagnostic value in genital warts compared to PCR among Women with Genital Lesions

Abstract

The aim of this study was to evaluate the frequency of HPV and determine the diagnostic value of anti-HPV in genital warts compared to PCR in women with genital lesions. Materials and Methods: In this cross-sectional study, 25 patients with genital lesions with genital warts were confirmed by HPR based on PCR (case group) and 25 patients with genital lesions were diagnosed with HPV PCR. Negative (control group) were included in the study (patients were female). Demographic information of patients including age, smoking (defined as having smoked a cigarette daily for at least 1 year), age at first sexual intercourse, number of sexual partners to date, number of warts, history of disease Background (diabetes, hypertension, hyperlipidemia, etc.), marital status, lesion site (intravaginal - extravaginal), history of sexually transmitted disease in the spouse, use of birth control pills, previous history of sexually transmitted disease were recorded. The above cases were compared between case and control groups. Results: The frequency of warts outside the uterus was higher than inside the uterus. Overall, the anti-HPV test was positive in 35 patients (70%). Sensitivity, specificity, positive predictive value and negative predictive value of Anti-HPV test were 84%, 44%, 60% and 73.33%, respectively. Young age at first sexual intercourse and lack of a history of STD in the individual are risk factors for HPV in the present study.