Comparing the efficacy of intravenous bolus Dexmedetomidine and mepridine on the treatment of shivering following general anesthesia

Abstract

Shivering after general anesthesia is one of the most common complications after anesthesia that leads to other unwanted complications; Various drugs have been considered to treat this complication, one of the newest of which is Dex Medomedin; For this purpose, in this study, the effect of dexamedomidine in the treatment of shivering after general anesthesia will be compared with one of the well-known drugs effective in the treatment of shivering, namely pethidine. Use routinely after anesthesia. Materials and Methods: This study was a clinical trial that was conducted during 2019-2020 with the participation of 100 patients who were candidates for abdominal surgery and required anesthesia in Imam Reza Hospital (Tabriz University of Medical Sciences). They were generalized and all of them were extubated after the surgery. For patients in the control group, 10 mg of pethidine was injected with chills and for patients in the intervention group, half micrograms / kg was injected after chills. Hemodynamic status of patients and their shivering intensity were measured and recorded every 5 . Results: The study of shivering intensity in the study participants showed that the standard deviation ± mean shivering intensity at the beginning of recovery in the pethidine group was 2.45 45 0.45 and in the dexmedetomedin group was 2.39 36 0.36 in both groups. Were statistically significant without difference; After drug injection, it was found that from ten minutes onwards, the standard deviation ± mean tremor intensity in the dexmedetomidine group was significantly reduced compared to the pethidine group. Standard deviation ± The mean duration of shivering in dexmedetomedine group was 18.55 33 1.33 minutes and in pethidine group was 24.15 2 2.15 minutes, which statistically dexmedetomedin group lost its shivering in a shorter time. Is (P = 0.009)