Association of ABO Blood Groups with baseline TIMI Flow of Culprit Vessel Patients and Incidence of Slow Flow in Patients with Acute ST-segment Elevation Myocardial Infarction undergoing Primary Percutaneous Coronary Intervention

Abstract

Primary PCI is currently recognized as the standard treatment for myocardial infarction with ST-segment elevation (STEMI). The aim of this study was to investigate the relationship between blood groups and baseline TIMI and the frequency of slow flow in the Culprit vessel in patients with acute myocardial infarction undergoing primary PCI. Materials and methods: In a cross-sectional study, 700 STEMI patients referred to Shahid Madani Educational-Medical Center of Tabriz University of Medical Sciences during the years 2017 to 2019 who had undergone primary PCI, were included the study. The records of all patients were reviewed and the study checklist including demographic information, angiographic findings of patients including involved vessel, main vessel involved, TIMI flow before and after primary PCI, no-reflow and slow reflow incidence were evaluated. Also, the final outcome of patients including in-hospital important complications such as mortality and bleeding was recorded based on the patients' clinical records. Results: 700 patients including 572 (81.71%) males and 128 (18.29%) females with a mean age of 58.84 ± 11.33 were included in the study. 30.46% of patients with normal TIMI and 32.25% of patients with impaired TIMI before PCI had blood type O, which was not statistically significant (P = 0.67). Based on flow after PCI surgery, 30.54% of patients with normal TIMI and 43.27% of patients with impaired TIMI had blood type O, which showed a significant difference (P = 0.01). Finally, 31.32% of patients with low grade thrombosis and 31.99% of patients with high grade thrombosis had blood type O, which was not statistically significant.