Determination and comparison of the antimicrobial property of chlorhexidine and nanosilver fluoride mouthwashes and the combined mouthwash on the amount of Salivary Streptococcus mutans in patients undergoing orthodontic treatment (Randomized clinical trial)

Abstract

Objective: The aim of this randomized clinical study was to investigate the efficacy of the nanosilver fluoride and chlorhexidine mouthwashes and their combinations on the Streptococcus mutans of saliva of the orthodontic patients. Materials and Methods: A total of 45 (n=15) orthodontic patients were included. The colony count of S. mutans bacteria of their saliva was counted before and after using mouthwash. The patients were divided into three groups of 15. Group 1 used chlorhexidine 0.2%, group 2 used nanosilver fluoride (0.005 Molar) and group 3 used the combination of these mouthwashes for 10 days. The data were analyzed using One way ANOVA and Tukey's test. Results: All mouthwashes reduced the CFU of S. mutans of saliva of the orthodontic patients (P< 0.05). No significant difference was found between the efficacy of chlorhexidine and nanosilver fluoride (P> 0.05). The best results were achieved by using the combination of nanosilver fluoride and chlorhexidine mouthwashes (P< 0.05). Conclusion: Combination of the nanosilver fluoride and chlorhexidine mouthwashes is a potential anti-carious mouthwash for orthodontic patients.