The Prevalence of Concurrent Acute Coronary Syndrome and their Associated Factors Among Patients Referred to Emergency Department with Early Diagnosis of Stroke

Abstract

A small number of stroke patients may present with concurrent ACS, which may be due to shared risk factors between the two disorders. Objectives. We aimed to evaluate the one-year prevalence of concurrent acute coronary syndrome (ACS) and its associated factors in patients presented with acute cerebral stroke at Imam Reza hospital, Tabriz, Iran. Methods. We included 896 adult patients admitted to the emergency department with a definite stroke diagnosis from 2018 to 2019. Data regarding demographics and previous medical history was collected, and the concurrent occurrence of ACS was assessed. Results. The mean (SD) age of subjects with hemorrhagic stroke was significantly lower than those with ischemic stroke or normal CT finding (p < 0.001). The previous history of oral contraceptive pill consumption and sleep apnea, and Modified Rankin Scale of four and more were more prevalent in those having CT finding of stroke than those with normal CT findings (p= 0.005, p=0.003, and p < 0.001, respectively). The prevalence of concurrent ACS was 1 %. The mean (SD) age and the prevalence of the previous history of ischemic heart disease and atrial fibrillation were significantly higher in subjects with concurrent ACS than those without concurrency (p= 0.035, p=0.023, and p=0.048, respectively). There was no significant association between baseline characteristics and concurrent ACS occurrence in patients with stroke after adjusting for confounders.